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Karen A. Pinco
Assistant Professor
Department of Biology
Westfield State College
Immunological Malfunction? 

This case study was developed to complement the study of the immune system and to emphasize the crosstalk that occurs at the cellular level between B and T cells for proper immune system function. In reading the story of a young couple trying to understand the cause of their infant boy’s constant bacterial infections, students review the different classes of antibodies, their specific functions, and how they arise through isotype switching. In addition, students apply their knowledge of basic genetics as they examine how X-linked disorders are passed along and the role of genetic counselors in medicine.