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William H. Cliff
Professor
bcliff@niagara.edu
Department of Biology
Niagara University
A Friend in Need is a Friend Indeed: A Case Study on Human Respiratory Physiology

This directed case study was designed to help students strengthen their understanding of the transport of oxygen in the blood through an analysis of the pathophysiology of a common, real-world problem, namely, carbon monoxide poisoning. The case was developed for use by undergraduates majoring in biology, nursing, and education who are enrolled in a two-semester course in human anatomy and physiology.


One Headache After Another: Biochemistry Edition 

Topamax®, developed to treat epilepsy, is also used as a preventative for migraine. In this case study, students read about a woman experiencing a side-effect of Topamax and from there move to a review of acid-base balance in the human body. The case study questions force the students to think about basic concepts related to buffers, pH, and equilibria, and challenge them to make specific connections. The case has two versions: one for chemists/biochemists and a second for physiologists. This is the biochemistry version.  Both versions cover acid-base balance to a similar extent, with the physiology version (titled "One Headache After Another: Physiology Edition") covering more of the factors involved with metabolic acidosis and exercise physiology. Both versions are geared to upper-level undergraduates.


One Headache After Another: Physiology Edition 

Topamax®, developed to treat epilepsy, is also used as a preventative for migraine. In this case study, students read about a woman experiencing a side-effect of Topamax and from there move to a review of acid-base balance in the human body. The case study questions force the students to think about basic concepts related to buffers, pH, and equilibria, and challenge them to make specific connections. The case has two versions: one for physiologists and a second one for chemists/biochemists (titled "One Headache After Another: Biochemistry Edition"). This is the physiology version.  Both versions cover acid-base balance to a similar extent, with the physiology version covering more of the factors involved with metabolic acidosis and exercise physiology. Both versions are geared to upper-level undergraduates.