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An Elderly Anomaly

A Realistic Integration of ECG, CBC, and PCR in Healthcare


Author(s)

http://sciencecases.lib.buffalo.edu/collection/detail.html?case_id=1068&id=1068
M. May Zhang
School of Pharmacy
University of Connecticut
ming.zhang@uconn.edu
Maria E. Latta
School of Pharmacy
University of Connecticut
maria.latta@uconn.edu

Abstract

This case study follows the process of diagnosing a patient, 67-year-old “Chester Fitzgerald,” who has suffered an ischemic stroke. An ECG is performed, but is not conclusive. During a physical exam, his doctor discovers a splenomegaly and orders a CBC to determine the cause. The results, combined with the other symptoms that Chester reports, lead the doctor to suspect an underlying disease rather than just an age-related stroke. This suspicion is confirmed by genetic testing, and the case closes with a brief description of a suitable treatment plan for the patient. The case walks students through multiple tests in the diagnosing process and aspects of healthcare to help them understand how these tests fit in the context of a real-life situation. The case study is divided into three parts that correlate with the three phases of this patient’s diagnosis. Each part ends with a series of questions designed to help students apply previous knowledge. The case study is appropriate for use in undergraduate anatomy and physiology courses.


Objectives

  • Recognize and describe the symptoms of polycythemia vera.
  • Label and interpret a normal ECG.
  • Distinguish between normal and abnormal measurements of an ECG.
  • Distinguish between normal and abnormal CBCs.
  • Recognize a patient with polycythemia based on his/her CBC, given reference values.
  • Recognize genetic mutations based on gene sequence.
  • Describe the steps of PCR.
  • Explain how a genetic mutation can cause cancer.
  • Explain why multiple tests may be necessary to diagnose a patient.

Keywords

Polycythemia vera; PV; ECG; EKG; complete blood count; CBC; splenomegaly; myeloproliferative neoplasms; PCR; genetic testing

Educational Level

Undergraduate lower division, Undergraduate upper division

Format

PDF

Type Methods

Directed, Interrupted

Language

English

Subject Headings

Anatomy Genetics / Heredity Physiology


Date Posted

11/13/2019

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