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Sometimes Less is Better

The Treatment of Thromboembolism



Co Authors:

Angela Wisniewski
Department of Family Medicine and Pharmacy Practice
University at Buffalo
amw25@buffalo.edu

Thuy N. Nguyen
Clinical Pharmacy and Pharmaceutical Economics & Policy
University of Southern California
t.nguyen@usc.edu

David Newberger
Department of Family Medicine
University at Buffalo
dsn@buffalo.edu

Abstract:

“Ed Cramer” is a 47-year-old mechanical engineer who is being treated for venous thromboembolism. He was 45 when he first developed a blood clot in the lower part of his left leg and had to be hospitalized for five days. A year later, he developed a second blood clot, which almost killed him. This case study explores the physiology and treatment of venous thromboembolism, a condition which kills 60,000 people each year in the United States. The case was developed for use in graduate-level courses in medicine and pharmacy.

Objectives:
  • To review the physiology and pathophysiology of the coagulation cascade.
  • To be introduced to contemporary developments in the treatment of venous thromboembolism.
  • To gain an appreciation of the statistical methodology employed, as well as analyzing in-depth the tables and charts provided in the article.
  • To conduct a thorough critical appraisal of an article in the current medical literature.
  • To apply knowledge gained and conclusions from the current medical literature to treatment decisions in a specific patient case.
Keywords: Venous thromboembolism; anticoagulation; coagulation cascade; Virchow's Triad; warfarin therapy
Topical Area: N/A
Educational Level: Graduate, Professional (degree program), Clinical education, Continuing education
Formats: PDF
Type/Method: Interrupted, Journal Article, Role-Play
Language: English
Subject Headings: Pharmacy / Pharmacology   Physiology   Medicine (General)  
Date Posted: 08/16/04
Date Modified: N/A
Copyright: Copyright held by the National Center for Case Study Teaching in Science, University at Buffalo, State University of New York. Please see our usage guidelines, which outline our policy concerning permissible reproduction of this work.

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