- Teaching Notes
Genetic Abnormalities and Tissue Donations
Lauren E. Yaich
In this case study about a baby born with the genetic condition holoprosencephaly, students explore the “Sonic hedgehog” gene, signal transduction, and the ethics of body and tissue donation. The assignment involves students writing an informed consent document that explains the science behind this congenital abnormality. Designed for an upper-level undergraduate biology course, the case could also be used in a cell biology, developmental biology, neurobiology, or other related upper-level course.
|Keywords:||Holoprosencephaly; Sonic hedgehog; Cyclops; brain development; signal transduction; cell signaling; birth defect; congenital defect; tissue donation; organ donation; medical research; bioethics|
|Topical Area:||Ethics, Legal issues, Social issues|
|Educational Level:||Undergraduate upper division|
|Subject Headings:||Cell Biology Neuroscience Genetics / Heredity|
|Copyright:||Copyright held by the National Center for Case Study Teaching in Science, University at Buffalo, State University of New York. Please see our usage guidelines, which outline our policy concerning permissible reproduction of this work.|
Case teaching notes are intended to help teachers select and adopt a case. They typically include a summary of the case, teaching objectives, information about the intended audience and how the case may be taught, a case analysis or answer key, and references.
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