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A Bad Reaction
A Case Study in Immunology
James A. Hewlett
This case involves the transfer of a food allergy to a patient who received a combined kidney and liver transplant from a donor who died as the result of an allergic reaction. In addition to learning about the various roles of immune cells, the physiology of anaphylaxis, and the function of antibodies in immune physiology, students explore concepts related to histocompatibilities, organ donation, and organ rejection. The case is appropriate for use in a course in human physiology, a combined course in human anatomy and physiology, or an introductory course in immunology.
|Keywords:||Allergic reaction; allergen; peanut allergy; anaphylaxis; antigen; antibody; major histocompatibility complex; MHC; human leukocyte antigen; HLA; immune response; organ donation; tissue donation; liver transplant; kidney transplant; organ rejection|
|Educational Level:||Undergraduate lower division, Undergraduate upper division|
|Subject Headings:||Physiology Medicine (General)|
|Copyright:||Copyright held by the National Center for Case Study Teaching in Science, University at Buffalo, State University of New York. Please see our usage guidelines, which outline our policy concerning permissible reproduction of this work.|
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