New search
download case
  • Overview
  • Teaching Notes
  • Answer Key
  • Comments/Replies

It’s All Greek to Me: Genetics Edition



Author:

Leslie G. Wooten
Biology Department
Tallahassee Community College
wootenl@tcc.fl.edu

Abstract:

Stephania and Nikolaus Stamos are concerned about their baby daughter. They take her to her pediatrician, who immediately notices that the once bright and active child is small for her age, pale, lethargic, and has a swollen abdomen. Students examine the patient's symptoms and test results, and then construct a pedigree chart and Punnett square to identify and understand the genetic disorder she is suffering from. Originally developed for a molecular biology course taken mostly by junior and senior undergraduate students, the case can be adapted for use in a course in cell biology, physiology, biochemistry, or genetics (see also the related "Physiology Edition").

Objectives:
  • Understand the importance of iron.
  • Learn about the structure and function of hemoglobin.
  • Learn about the normal and abnormal morphology of red blood cells.
  • Be able to recognize normal versus abnormal CBC (complete blood count) results.
  • Learn about the transmission of an inheritable disease based on Punnett square and pedigree analysis.
  • Learn about the importance of pedigree construction in genetic counseling.
Keywords: Cooley's anemia; beta-thalassemia; genetic diseases; genetic disorder; hemoglobin; blood; red blood cells; CBC; iron; mRNA processing error; transcription; translation; mutation; pedigree; Punnett square; genetic counseling
Topical Area: N/A
Educational Level: Undergraduate lower division, Undergraduate upper division
Formats: PDF
Type/Method: Discussion, Interrupted
Language: English
Subject Headings: Genetics / Heredity   Cell Biology   Molecular Biology   Biology (General)   Medicine (General)  
Date Posted: 2/21/2012
Date Modified: N/A
Copyright: Copyright held by the National Center for Case Study Teaching in Science, University at Buffalo, State University of New York. Please see our usage guidelines, which outline our policy concerning permissible reproduction of this work.

Teaching Notes


Case teaching notes are password-protected and access to them is limited to paid subscribed instructors. To become a paid subscriber, begin the process by registering here.

Teaching notes are intended to help teachers select and adopt a case. They typically include a summary of the case, teaching objectives, information about the intended audience, details about how the case may be taught, and a list of references and resources.

  Download Teaching Notes

Answer Key


Answer keys for the cases in our collection are password-protected and access to them is limited to paid subscribed instructors. To become a paid subscriber, begin the process by registering here.


  Get Answer Key



Name:
Email:
Department:
Institution:
City State:
Comments:
security code
Enter Security Code: