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A Rough Semester

What's Wrong with Katie?


Author(s)

Thomas E. Hynd
Biology Department
James Madison University
hyndte@jmu.edu
Elizabeth V. Berkeley
Department of Biology and Earth Science
Otterbein University
eberkeley@otterbein.edu
Janet C. Daniel
Biology Department
James Madison University
danie2jc@jmu.edu
Justin W. Brown
Biology Department
James Madison University
brown3jw@jmu.edu
Bisi T. Velayudhan
Biology Department
James Madison University
velayubt@jmu.edu

Abstract

This interrupted case study tells the story of Katie, an active college sophomore who experiences flu-like symptoms.  She initially thinks that her illness is a result of the stress associated with the rigors of college; however, after visiting her university's health center and subsequent treatment with typical flu remedies, her symptoms worsen and multiply.  After several clinical tests, Katie is diagnosed with type II diabetes mellitus and given appropriate treatment. The case includes a lab component (which can be eliminated with minor modifications) in which students complete a urinalysis of a sample of Katie's "urine" by testing for glucose, hemoglobin and pH with commercially available urinalysis reagent test strips, and measure specific gravity with a refractometer. This case was designed for a one-semester, introductory physiology laboratory course taken mainly by sophomore/junior pre-nursing and health science students, but could also be used in a more advanced physiology course for biology students.


Objectives

  • Develop critical thinking skills by analyzing and interpreting data.
  • Identify pertinent red flags in a medical history.
  • Interpret basic medical test results.
  • Understand how glucose and protein are processed by the kidney.
  • Understand the physiology of insulin.
  • Explain the pathophysiology and potential treatments of type II diabetes mellitus.
  • Describe how several commonly prescribed treatments of type II diabetes mellitus counter the underlying pathophysiology of the disease.
  • Understand that drugs have contraindications, which exclude them from being prescribed in certain patients.
  • Describe the physiologic relevance of hemoglobin A1c in treating type II diabetes mellitus.

Keywords

Kidney; urinalysis; diabetes; laboratory; diabetes; diabetes mellitus; insulin; glucose; lipid panel; cbc; Canagliflozin; SGLT2

Topical Areas

N/A

Educational Level

Undergraduate lower division, Undergraduate upper division, Clinical education

Format

PDF

Type / Methods

N/A, Interrupted, Laboratory

Language

English

Subject Headings

Cell Biology  |   Medicine (General)  |   Nursing  |   Pharmacy / Pharmacology  |   Physiology  |  


Date Posted

3/18/2019

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