Those Old Kentucky Blues
An Interrupted Case Study
Department of Biology & Zoology
The University of British Columbia
University of Virginia
This interrupted case study begins with the construction of a pedigree following an initial encounter with a clan of “blue people.” After constructing a pedigree, students decide whether the condition (methemoglobinemia) is a heritable trait. Students are then exposed to a different perspective of this condition and have to re-evaluate the inheritance pattern. This case study was written for a first year honors course in general biology. It could be modified for most general science majors’ biology, genetics, biochemistry, and cell biology courses.
- Hypothesis generation.
- Pedigree construction and analysis.
- Evaluation of inheritance patterns.
- Reconciliation of changing inheritance patterns, depending on perspective.
KeywordsMendelian inheritance patterns; phenotype; incomplete dominance; pedigree; skin color; enzyme; hemoglobin; methemoglobinemia; Kentucky; Appalachian Mountains
Topical AreasScientific method
Educational LevelHigh school, Undergraduate lower division
Type / MethodsInterrupted
Subject HeadingsBiology (General) | Biochemistry | Cell Biology | Genetics / Heredity |
Case teaching notes are password-protected and access to them is limited to paid subscribed instructors. To become a paid subscriber, begin the process by registering.
Teaching notes are intended to help teachers select and adopt a case. They typically include a summary of the case, teaching objectives, information about the intended audience, details about how the case may be taught, and a list of references and resources.