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Those Old Kentucky Blues

An Interrupted Case Study


Author(s)

Celeste A. Leander
Department of Biology & Zoology
The University of British Columbia
cleander@interchange.ubc.ca
Robert J. Huskey
Biology Department
University of Virginia

Abstract

This interrupted case study begins with the construction of a pedigree following an initial encounter with a clan of “blue people.” After constructing a pedigree, students decide whether the condition (methemoglobinemia) is a heritable trait. Students are then exposed to a different perspective of this condition and have to re-evaluate the inheritance pattern. This case study was written for a first year honors course in general biology. It could be modified for most general science majors’ biology, genetics, biochemistry, and cell biology courses.


Objectives

  • Hypothesis generation.
  • Pedigree construction and analysis.
  • Evaluation of inheritance patterns.
  • Reconciliation of changing inheritance patterns, depending on perspective.

Keywords

Mendelian inheritance patterns; phenotype; incomplete dominance; pedigree; skin color; enzyme; hemoglobin; methemoglobinemia; Kentucky; Appalachian Mountains

Topical Areas

Scientific method

Educational Level

High school, Undergraduate lower division

Format

PDF

Type / Methods

Interrupted

Language

English

Subject Headings

Biology (General)  |   Biochemistry  |   Cell Biology  |   Genetics / Heredity  |  


Date Posted

3/4/2008

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