Make a Life to Save a Life
Department of Plant Biology
University of Georgia
In this “clicker case,” students learn about meiosis through the real-life story of a couple who used pre-implantation genetic screening to select an embryo that was a genetic match for an older sibling with leukemia, and thus able to provide a source of bone marrow cells. The case caused a stir in the medical ethics community. Before this, parents had only used pre-implantation genetic screening to select for a baby that would be free from a genetic disorder. Instead, this child was conceived as a treatment for his older sister. The case was developed for use in an introductory biology course. It consists of a PowerPoint presentation (~1.5MB) shown in class that is punctuated by multiple-choice questions the students respond to using clickers. It could be adpated for use without these technologies.
- Understand how chromosomes are distributed during meiosis to create variation in the gametes produced.
- Understand how the genetic information in a gamete differs from the information found in other somatic cells of the parent and how gametes differ from each other.
- Apply knowledge of how chromosomes are segregated during meiosis to predict the likelihood that an offspring from two parents would inherit a specific combination of chromosomes.
KeywordsMeiosis; cell division; independent assortment; pre-implantation genetic screening; embryo design; reproduction; organ donation; bioethics; medical ethics
Topical AreasEthics, Policy issues, Social issues
Educational LevelHigh school, Undergraduate lower division
Type / MethodsClicker, Interrupted
Subject HeadingsBiology (General) | Cell Biology | Genetics / Heredity | Medicine (General) |