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Antibiotic Resistance

Can We Ever Win?


Author(s)

Maureen Leonard (rr)
Biology
Mount Mary University

Abstract

Resistance to antibiotics arose very shortly after these "wonder drugs" were first introduced.  This case study examines resistance to the most commonly used antibiotics, penicillin and its derivatives.  In particular, it examines a recent study that shows potential for restoring susceptibility to these antibiotics in MRSA (methicillin-resistant Staphylococcus aureus).  The case provides students with opportunities to collect and analyze data as well as interpret data from the new study.  The case was designed for use in an introductory college level biology or microbiology course.  Measuring, calculating means and standard errors, and graphing techniques are included, and this case can be used to introduce them or serve as practice.  The case can also be used in upper-level courses for the purpose of practicing data collection and analysis.


Objectives

  • Practice the scientific method, with emphasis on asking scientific questions and deciding what data are appropriate to answer them.
  • Demonstrate organized data collection for students by allowing students to practice measurement and data collection, perform simple data analyses such as means and standard errors, and graph and interpret results.
  • Introduce or review enzyme function and bacterial cell wall structure.
  • Introduce the problem of antibiotic resistance and describe some alternate approaches in dealing with it.

Keywords

Antibiotic resistance; methicillin-resistant Staphylococcus aureus; MRSA; antibiotics; penicillin; methicillin; data analysis

Educational Level

High school, Undergraduate lower division, Undergraduate upper division

Format

PDF

Type Methods

Discussion, Interrupted

Language

English

Subject Headings

Biology (General)  |   Microbiology  |   Evolutionary Biology  |   Medicine (General)  |   Science (General)  |   Public Health  |  


Date Posted

12/3/2012

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