Dr. Collins and the Case of the Mysterious Infection
Division of Biological Sciences
University of Georgia
Department of Fisheries Science
The College of William & Mary
In this case study, Dr. Collins must diagnose and prescribe treatment for a young patient with a serious infection. Students receive pieces of the case in a progressive disclosure format and answer questions about bacterial infection, antibiotics, and antibiotic resistance. The case was designed for the seminar component of a large-enrollment, introductory biology course. In addition to seminar, students in the course also attend lecture and laboratory. Teaching assistants lead the 12-student seminars, during which students engage in directed inquiry exercises such as this case.
- Describe some of the biochemical mechanisms by which antibiotics act against bacteria.
- Evaluate which antibiotics would be effective against a given type of bacteria.
- Apply basic knowledge of DNA, genes, and proteins (and the relationship between them) to a new question, i.e., how do changes in DNA observed by pulsed-field gel electorophoresis impact patterns of antibiotic resistance?
- Synthesize the relationship between antibiotic consumption and antibiotic resistance based on what’s been learned about bacteria, antibiotics, and natural selection.
- More adeptly use data from charts and gels to answer questions.
KeywordsAntibiotics; antibiotic resistance; bacteria; infection; infectious disease; pulsed-field gel electrophoresis
Educational LevelHigh school, Undergraduate lower division, General public & informal education
Type / MethodsInterrupted
Subject HeadingsBiology (General) | Microbiology | Public Health |
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