A Case of Respiratory Distress
Department of Science
Borough of Manhattan Community College / City University of New York
Ambulatory Care Department
Jamaica Hospital Medical Center
This clinical case study was developed to engage students by making connections between core concepts in chemistry and physiological processes in the body. The case pertains to medication-induced methemoglobinemia, its etiology, diagnosis, and treatments. Concepts taught by the case include the use of conversion factors, pH, buffering, Le Chatelier's principle, blood chemistry, and respiratory and metabolic acidosis and alkalosis. The case is suitable for use in a General, Organic, and Biological (GOB) Chemistry course or other introductory general chemistry course as well as undergraduate physiology courses. The case also could be adapted for use in undergraduate pharmacology and medicinal chemistry courses.
- Use conversion factors in determining possibility of pneumonia and dosage of medication.
- Apply pH, buffering, and Le Chatelier's principle to blood chemistry.
- Understand the principles underlying respiratory and metabolic acidosis and alkalosis.
- Understand the etiology, manifestation, diagnosis, and treatment of methemoglobinemia.
KeywordsAcidosis; alkalosis; blood chemistry; buffering; conversion factors; Le Chatelier’s principle; methemoglobinemia; methylene blue; oxygen therapy; pH; pulse oximetry; respiratory distress
Educational LevelUndergraduate lower division, Undergraduate upper division
Type / MethodsDirected
Subject HeadingsChemistry (General) | Organic Chemistry | Biochemistry | Medicinal Chemistry | Physiology | Pharmacy / Pharmacology |