Hemophilia
The 'Royal Disease'
Author(s)
Abstract
This case deals with the genetics of the hemophilic condition that afflicted the royal families of Europe. Students trace the pedigrees of the descendants of Queen Victoria and the passage of the recessive X-linked trait from ancestor to ancestor. The case is suitable for courses in general biology at either the high school or college level.
Objectives
- Provide a real example of pedigree analysis of a sex-linked trait.
- Provide students an opportunity to calculate probabilities of the transmission of a genetic trait.
Keywords
Hemophilia; haemophilia; hemophiliac; recessive disorder; genetic disease; sex-linked trait; blood; hemoglobin; Queen Victoria; Tsarevich Alexei Nikolaevich; RomanovsTopical Areas
N/AEducational Level
High school, Undergraduate lower divisionFormat
PDFType / Methods
Directed, Discussion, InterruptedLanguage
EnglishSubject Headings
Genetics / Heredity | Biology (General) | Medicine (General) |
Date Posted
05/1/99Teaching Notes
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Answer Key
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