Skip to Content

Search Results

Records returned 90

A Can of Bull

This case study is designed to teach students at various levels about large biomolecules, nutrition, and product analysis. Students conduct a bioch ...


A Case of Medication Error

This case study begins with a real news article about a six-month-old baby who died from an overdose of medication administered by hospital staff. ...


A Case of Respiratory Distress

This clinical case study was developed to engage students by making connections between core concepts in chemistry and physiological processes in t ...


A Curious Mission: An Analysis of Martian Molecules

In this case study, students play the role of a NASA scientist tasked with analyzing samples of atmosphere and soil collected on Mars as part of th ...


A Diet to Die For

This clicker case is designed to lead students to a conceptual understanding of oxidative phosphorylation (and, by analogy, photosynthesis). Studen ...


A Light Lunch?

This case study was developed to engage students by making connections between core concepts in chemistry and obesity related factors. The case is ...


A Perfect Storm in the Operating Room

In this interrupted case study, a high school biology student shadows her uncle, an anesthesiologist, at a hospital for a school assignment. She wi ...


A Rainbow of Sepia

This flipped case study examines the selective pressures that have affected the evolution of diverse human skin pigmentations. To prepare for the c ...


A Rigorous Investigation

In this directed case study, students investigate the cause of death in an incident that occurs late at night in a research lab. The overall goal o ...


A Sickeningly Sweet Baby Boy

When a newborn develops symptoms eerily similar to those of an older sibling who died shortly after birth, his Mennonite parents are understandably ...


A Tragic Finding

This interrupted case study utilizes real patient data and provides students an opportunity to apply knowledge of human metabolism and hormonal con ...


A Yellow-Bellied Lawyer?

This interrupted case study tells the story of Michael, a Harvard law graduate with a stressful job and a seemingly heavy drinking problem. Student ...


Acids, pH, and Buffers

In this “clicker case,” a three-year-old girl gets into the medicine cabinet and ingests an unknown number of aspirin tablets. Her brot ...


African Illness: A Case of Parasites?

This case is based on a British patient presenting to a hospital with an array of symptoms after returning from an African safari. Students learn a ...


Agony and Ecstasy

This interrupted case study explores the scientific, legal, and societal complexities of repurposing an illicit substance, 3,4-methylenedioxymetham ...


Aliens on Earth?

The discovery of a bacterium capable of substituting arsenic for phosphorus in its DNA was announced with much fanfare in 2010. It was immediately ...


Am I a Girl, or a Boy?

A baby is born with ambiguous genitalia to parents from the Dominican Republic and is determined to be a female based on general appearance.  ...


Amanda's Absence

When chronic pain forces a top student to withdraw from college, biology instructor Dr. Sharpe learns that medications (in this case, Vioxx) may be ...


An Adventure in Stereochemistry

Playfully alluding to Lewis Carroll’s tale of Alice Through the Looking Glass, this case study considers the problems that would ari ...


An Infectious Cure

This four-part interrupted case on phage therapy was developed for a freshmen non-majors course in molecular biology. The case begins with a story ...


Another Can of Bull?

This case is a “clicker” adaptation of a similarly titled case by Merle Heidemann and Gerald Urquhart of Michigan State University, &ld ...


Bad Fish, Bad Bird

This "clicker case" is based on the General Biology edition of James Hewlett’s “Bad Fish” case in our collection. The case follow ...


Bad Fish: General Biology Edition

In this version, developed for a course in general biology, the protagonist of the case, Dr. Westwood, survives an accidental poisoning-not once, b ...


Bilirubin

In this case study, two students meet a professor who surprises them by telling them that a biochemically important molecule’s structure has ...


Biological Terrorism

In the weeks following the September 11, 2001, terrorist attacks on the World Trade Center and the Pentagon, anthrax-laced envelopes were mailed t ...


Breast Cancer Risk

This case study takes a combined directed and discussion approach to explore risk factors for breast cancer. After a preparatory reading assignment ...


Cats Have Nine Lives, But Only One Liver

In this case, a college student gives her cat Tylenol not knowing its potential harmful effects. The cat survives, but the incident motivates her ...


Caught Red-Handed

Was the "Brooklyn Butcher" of 1926 a cold-blooded killer or was something less sinister at play? This interrupted case study introduces students to ...


Diabetes and Acid/Base Chemistry

This case study focuses on a teenage patient with type 1 diabetes mellitus (T1DM) who presents with severe acidosis, becomes combative and loses co ...


Diabetes and Insulin Signaling

Cellular signaling, otherwise known as signal transduction, is the mechanism by which cellular context and environmental situation are used to regu ...


Do Grasshoppers Sweat?

There are many adaptive and evolutionary behaviors displayed in an organism's use of water. Although students generally have a superficial understa ...


Evolution in Action

This case study is based on Dr. Richard Lenski’s ongoing studies of evolution in E. coli. Students are introduced to prokaryotic bio ...


Face the Fats

This clicker case introduces students to the biochemistry of lipids through the story of Pete, a college student who begins to consider his nutriti ...


Fat Facts

It's Mother's Day and Dolly, a high school senior, is making a Mediterranean salad for her mom, who is a college chemistry major and who likes to t ...


From Cow Juice to a Billion Dollar Drug, With Some Breakthroughs in Between

Before the discovery of insulin in 1921, being diagnosed with Type 1 diabetes was a death sentence. Despite the successful management of diabetes w ...


From Prairies to Corn Fields for Fuel

With increasing U.S. government support for biofuel production in the late 2000s came increased pressure to convert more land to cornfields for eth ...


From Twiggy to Tubby

This case study explores the topics of diffusion, osmosis, membrane transport, and the physiological significance of glucose and insulin in the hum ...


Holes in the Matter

This case centers on a fictional group of young adults who studied abroad together in Scotland as college students. A number of them develop diseas ...


How to Make ATP

This case study for the flipped classroom introduces the discovery process used to elucidate how cells make ATP. Data from three seminal primary li ...


I Scream for Ice Cream

Lactose intolerance, caused by a lack of persistent lactase enzyme expression, is a trait commonly observed in adult humans, with varying geographi ...


In Search of a Cure for Breast Cancer

In this directed case study, students analyze data, draw a research-based conclusion, interpret experimental results, and discuss the relevance of ...


Joel E. Greengiant Learns About Peas

This case study follows purveyors of peas, Joel E. and Jolene Greengiant, as they learn about the origin, biochemistry, genetics and eventual artif ...


Kermit to Kermette?

This case study explores the unintended side effects of chemicals introduced into the environment, specifically organic compounds that can act as e ...


Making Connections

This case study introduces students to Duchenne muscular dystrophy (DMD) and its underlying genetics, cell biology, and some of the associated ...


Metabolism Out of Control

Cancer is a complex and varied group of diseases. There are, however, several common characteristics among all cancers. For example, it has been kn ...


Monarchs and Milkweed

This interrupted case study was written to help students understand the interplay and relatedness of metabolism in producers and consumers. The sto ...


Monday on the Metabolic Ward

This case is a variation of a longer case in our collection titled "Murder or Medical Mishap? Death on the Metabolic Ward," which has a "murder-mys ...


Mother's Milk Cures Cancer?

This case study on the immune system, cell cycle regulation, and cancer biology explores the role that serendipity plays in new discoveries in scie ...


Murder or Medical Mishap?

In this "clicker case," students assume the role of pre-med students participating in a summer internship. As interns, they diagnose several differ ...


New Ways to Breathe

This case study follows a young cystic fibrosis (CF) patient named Lucas. Through Lucas's story and interactions between his parents and pediatrici ...


Newsflash! Transport Proteins on Strike!

This role-play case study teaches students about plasma membrane transport and the functions of transport proteins in the phospholipid bilayer. Stu ...


No Matter If You’re Black or White

Human populations have adapted to varying intensities of sunlight with varying tones of skin coloration. The balanced interplay between melanin con ...


Oh, What a Difference a Carbon Can Make!

Sarah, trapped in the middle of a two-hour lecture on enzyme inhibition, attempts to escape by asking a question. She relates an old story she hear ...


One Headache After Another: Biochemistry Edition

Topamax®, developed to treat epilepsy, is also used as a preventative for migraine. In this case study, students read about a woman experiencin ...


Pharmacogenetics: How Genetic Information Is Used to Treat Disease

In this clicker case, two teenagers are diagnosed with Acute Lymphoblastic Leukemia (ALL), a cancer of the bone marrow where there is an abnormal o ...


Properties of Gases: A Case Study of the Bends

In 2012, Mike Prickett, a world-renowned underwater cinematographer, was working on a commercial photo shoot in Tahiti when he witnessed a fellow d ...


Rice ’n Beans or Ricin Beans?

Taylor must write a report about a natural toxin while she is home from college on break. After a family dinner conversation about the latest attem ...


Rough Games and the Brain

In this "clicker case study," students learn about the chemical nature of protein molecules-in particular, how the constituent parts of proteins (a ...


Should Bill Buy Sammy?

In this case, students are shown the relevance of chemistry in daily decision-making by taking a look at the popular dietary supplement, s-adenosyl ...


Sickle Cell Anemia

In this case study on sickle cell anemia, students are introduced to some of the key researchers responsible for determining the molecular basis of ...


Snow White Apples?

The protagonist of this two-day flipped case study, “Maria,” has two problems. She doesn’t like it when the apple slices in her l ...


Statins Stat!

This case study describes a visit by "Naomi" to her physician, who upon seeing Naomi's bloodwork decides to prescribe her a cholesterol-lowering ag ...


Stomp the Stomach Bug

Norovirus is one of the most common causes of infectious diarrhea and vomiting, leading to the nickname “winter vomiting disease.” The ...


Sweet Indigestion

These days it seems like everyone is counting carbs. About 24 million Americans report they have cut carbohydrates from their diet, and 44 million ...


Sweet Truth

This case reviews concepts of monosaccharide, disaccharide, and polysaccharide and contrasts the structures of different pairs of carbohydrates as ...


The Campus Coffee Shop

Since caffeine is a widely used substance, especially by college age students, this case on the effects of caffeine on the human body serves as a r ...


The Case of the Missing Bees

Colony Collapse Disorder (CCD) has claimed approximately one-third of the commercial honeybee population in recent years. A number of causes have b ...


The Case of the Tainted Taco Shells: Advanced Edition

This case discusses some of the issues associated with the use of genetically modified plants, including ecological risks, resistance, and allergen ...


The Case of the Tainted Taco Shells: General Edition

This case discusses some of the issues associated with the use of genetically modified plants, including ecological risks, resistance, and allergen ...


The Chemistry of Cocaine

This case study on the chemistry of cocaine is in the form of a classroom discussion between a professor and her students about cocaine, its addict ...


The Chemistry of Cooley's Anemia

Young parents, Max and Andrea Forest, learn that their child is suffering from the genetic disorder, thalassemia. Treatment requires a lifetime com ...


The Chemistry of Curcumin

This case study was developed to engage students by making connections between core concepts in organic chemistry and the health-promoting chemical ...


The Cold Never Bothered Me Anyway

Woolly mammoths and other cold-adapted animals, such as reindeer and musk ox, developed a number of adaptations that allowed them to survive in fri ...


The Fun in Fermentation

When covering the process of cellular respiration, advanced high school and undergraduate biology classes present fermentation as a means of anaero ...


The Interview: Hemoglobin vs. Myoglobin

This case study examines the structure of hemoglobin and myoglobin and how the structure of these molecules dictates their function. The case is wr ...


The Mermaid and the Globins

The function and regulation of hemoglobin is often difficult for students to understand. This directed case study is an attempt to make the topic m ...


The Modern Caveman’s Dilemma

During the Paleolithic era, human life expectancy was only 33 years—roughly half of what it is today. We owe our more extended lives in part ...


The Molecular Origin of Life: Replication or Metabolism-First? Advanced Version

This case explores both the evidence and inconsistencies in the two major hypotheses for the origins of life on Earth: Replication-First or Metabol ...


The Mona Lisa Molecule: Mysteries of DNA Unraveled

This case study details the historical discovery of the structure of DNA. Images of this key molecule are as iconic as those of the Mona Lisa, and ...


The Secret of Popcorn Popping

Focusing on the important role of water in living cellular chemistry, this case emphasizes the general solubility rule, "like dissolves like," whic ...


The Spark of Life

In biology classes, students are typically taught that spontaneous generation does not take place. And yet, at the origin of life, life had to aris ...


Thiamin Deficiency

In this directed case study developed for a biochemistry class, students read about the differences in the dietary preferences and practices for pr ...


Those Old Kentucky Blues

This interrupted case study begins with the construction of a pedigree following an initial encounter with a clan of “blue people.” Aft ...


To Be or Not to Be ... an Inhibitory Neurotransmitter

Jessica and George are students struggling to understand the forces which control ions moving across membranes.  For the nervous system in par ...


Toxic Circumstances

This interrupted case study tells the true story of Karl P. Schmidt, a herpetologist and museum curator who was bitten by a venomous snake in 1957. ...


Vikings on Mars

Three experiments carried out by the Mars Viking landers in 1976 remain, to this day, our only attempt to detect life on another planet. All other ...


Why is Patrick Paralyzed?

This “clicker case” introduces students to a rare genetic disease in which an enzyme is deficient in a critical metabolic pathway&mdash ...


Wiggles Isn’t Wiggling: Apoptosis Edition

This case study tells the story of a family pet that is diagnosed with cancer.  Claire learns that her dog Wiggles has lymphoma, and that hist ...


Wiggles Isn’t Wiggling: Gene Expression Edition

This case study tells the story of a family pet that is diagnosed with cancer.  Claire learns that her dog Wiggles has lymphoma, and that hist ...


Yvette's Brave Battle

This case is based on the true story of a woman with choriocarcinoma, a rare type of rapidly dividing and metastatic cancer derived from cells of t ...