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A Question of Responsibility

Most students are aware that asbestos is a health hazard, but don’t know that “asbestos” refers to a variety of minerals with bot ...


A Simple Plan

This case study introduces students to Dr. E.L. Trudeau, who performed a seminal early experiment validating the germ theory of infection. Part I i ...


A Yellow-Bellied Lawyer?

This interrupted case study tells the story of Michael, a Harvard law graduate with a stressful job and a seemingly heavy drinking problem. Student ...


African Illness: A Case of Parasites?

This case is based on a British patient presenting to a hospital with an array of symptoms after returning from an African safari. Students learn a ...


Anencephaly in Yakima

This case study explores the recent (2010 - 2016) outbreak of neural tube defects, specifically anencephaly, in a rural three-county region of Wash ...


Antibiotic Resistance in a Russian Prison

In this case study, students will have the opportunity to model the spread of tuberculosis and development of antibiotic resistance in a hypothetic ...


Black and Blue with Love

In this directed case study students follow a nurse practitioner and work with a diagnostics team to determine what is wrong with Tristan, an infan ...


Blake's Illness

Blake is sick.  With his background in the sciences and a little help from the Internet, he should be able to do a self-diagnosis.  Or ca ...


Breast Cancer Risk

This case study takes a combined directed and discussion approach to explore risk factors for breast cancer. After a preparatory reading assignment ...


Buzz Off!

This case study was written to teach students about malaria, an infectious disease transmitted by the female Anopheles mosquitoes that thr ...


CAMEL Question: Can Applied Math Extend Life?

This directed case study examines differences between the exponential and logistic growth models in biology and how they are applied to solve real ...


Campus Outbreak!

This PowerPoint-driven case study follows the progress of three undergraduate students as they attempt to model the rapid spread of an influenza ou ...


Cancer Cluster or Coincidence?

In this interrupted case study students analyze the complexities surrounding identification and confirmation of cancer clusters. The case challenge ...


Childbed Fever

This case describes the pioneering work of Ignaz Semmelweis and his efforts to remedy the problem of childbed fever in mid-19th century Europe.&nbs ...


Chimpanzee Droppings Lead Scientists to Evolutionary Discovery

This interrupted case study focuses on the research of Dr. Beatrice Hahn, who investigates DNA sequences in chimpanzee droppings in order to explor ...


Cholera and Conflict in Yemen

This case study explores the 2016–2018 cholera outbreak in Yemen and how political and financial circumstances impacted relief efforts. Stude ...


COVID-19

In this directed case study, students assume the role of investigators for the Centers for Disease Control and Prevention (CDC) as they examine and ...


Cracking the Case

In this directed case study, students shadow Dr. Lee in diagnosing two patients with osteoporosis. The students are given patient history and an in ...


Danielle's Difficulty

The incidence of Clostridium difficile infection (CDI), including severe infection, has increased in both institutional settings and the g ...


Disease Along the River: A Case Study and Cholera Outbreak Game

This case study centers on an active teaching game that simulates a cholera outbreak among five villages along a river, similar to the Haitian outb ...


East Meets West

Ying is sick and is progressively getting worse. His parents' clashing views on Eastern and Western medicine prevent them from agreeing on a course ...


Eating PCBs from Lake Ontario - Is There an Effect or Not?

This case is based on an actual news release reporting on research about the effects of eating Lake Ontario fish contaminated with PCBs. Developed ...


Eating PCBs from Lake Ontario - The Clicker Version

This is a “clicker” adaptation of another case in our collection, “Eating PCBs from Lake Ontario: Is There an Effect or Not?&rdqu ...


Enigma in the ED

This PowerPoint-driven case study has students apply the “Steps of an Outbreak Investigation” from the Centers for Disease Control and ...


Fear!

In this PowerPoint-driven case study, students compare and contrast poliovirus and its effects with SARS-CoV-2/COVID-19. Before the class meeting, ...


Gastronomic Gastroenteritis at The Fat Duck

This interrupted case study was inspired by and uses data from one of the largest commercial restaurant associated outbreaks of norovirus reported ...


Headaches, Mood Swings, and Dropping Things

This interrupted case study walks students through the stages of determining a diagnosis for a neural condition/disease in a 62-year-old female. Th ...


Holes in the Matter

This case centers on a fictional group of young adults who studied abroad together in Scotland as college students. A number of them develop diseas ...


Hunting the Ebola Reservoir Host

This one-hour introduction to the study of infectious diseases uses recent research on the Ebola reservoir host to motivate students to consider th ...


Is it a Lemon or a Lyme?

This dilemma case was designed for a junior level immunology course. It could also be used in a microbiology or bacteriology course where the empha ...


Is There a Relationship Between Blood Type and Risk of Contracting COVID-19?

This directed case study introduces the basics of blood typing and discusses possible correlations for contracting COVID-19 by blood type. After st ...


It Takes a Herd

This directed case study places students in the role of committee members tasked with developing a strategic long-term plan for building up herd im ...


Know Your Enemy, Know Yourself

This case study relates the actual experiences of a woman with breast cancer as she shares her experiences through a series of blog posts at variou ...


Living the Sweet Life

In this directed case study, students help “Dr. Gupta” diagnose three patients in an endocrinology clinic who are having problems with ...


Microbial Pie, or What Did You Feed the Neighbors?

The Emergency Room seems busier than usual, and the cases coming in are all too similar.  Everyone seems to be suffering from the same symptom ...


MRSA in the NICU

DNA sequencing and analysis (bioinformatics) is an increasingly important tool for understanding biological data, including medical data. In this c ...


No Longer Living the Sweet Life

In this interrupted case study, students will help “Dr. Gupta” investigate and assess complications arising in one of her long-term pat ...


Oil in the Amazon

In this case study, students participate in a game in which they assume the roles of various stakeholders in a proposed oil and gas proje ...


Patient Zero

Emerging diseases and potential pandemics make the news nearly every year. Students (and everyone else) may wonder where new infectious diseases co ...


Proper Preparation

In this case study, students assume the role of health officials tasked with communicating to the public about the COVID-19 pandemic caused by seve ...


Return of the Whoop!

This interrupted case study outlines the history of pertussis or whooping cough, a disease that in the early 1900s claimed the lives of more people ...


Salem's Secrets

This case study examines the Salem witch trials that took place in Salem, Massachusetts, in the late 1600s. It is designed to provide students with ...


Sarah's Sickness

This story is based on the true account of a student who suffered years of misdiagnoses of her illness while she was in a professional school. As t ...


Social Distancing in the Midst of COVID-19

This directed case study is intended to give students insight into why social distancing is used to minimize the spread of infectious diseases. Stu ...


Statins Stat!

This case study describes a visit by "Naomi" to her physician, who upon seeing Naomi's bloodwork decides to prescribe her a cholesterol-lowering ag ...


Streams of Coal or Streams of Death?

Mary Beth was raised in Western Pennsylvania, an area where thousands of abandoned coal mines have led to extensive contamination of streams and a ...


Sunny Skies and a Lurking Microbe

Based on a true story, this case study chronicles the development of a wound infection that began as a minor cut that occurred while carrying out a ...


The 1st New Disease of the 21st Century

This case study uses a PowerPoint (~1MB) combined with role-playing to present the epidemiology and pathophysiology of Severe Acute Respiratory Syn ...


The Case of a Tropical Disease and its Treatment

This case study highlights the epidemiological and socioeconomic factors associated with a disease which plagues thousands of people in Central and ...


The Case of the Newborn Nightmare

Three newborns left in the care of "Dr. Mark Maddison" have developed a mysterious rash. Under increasing pressure from hospital administrators and ...


The Mystery of the Blue Death

This historical case study describes the story of John Snow’s discovery of water-borne transmission of cholera in 19th-century London. Design ...


The Path of a Pathogen

Scientists and healthcare professionals initially exhibited little concern over the Zika virus even after evidence of human infection was first ide ...


The Unfortunate Nurse

Dengue (pronounced "deng-ee") is a viral disease transmitted by the bite of an infected mosquito, usually Aedes aegypti. It is common in ...


Tragic Choices: Autism, Measles, and the MMR Vaccine

This case explores the purported connection between vaccines in general, and the MMR vaccine specifically, and autism. Students examine results fro ...


What Should the Victor Do with the Vanquished?

Smallpox, the worst infectious disease mankind has known, represents a major triumph as the first disease to be intentionally and completely remove ...


Where’s the Evidence?

This analysis case study uses a jigsaw activity in which students learn about characteristics of the novel coronavirus causing COVID-19, SARS-CoV-2 ...


Why Was the 1918 Influenza So Deadly?

In this intimate debate, students examine the causes of the devastation wrought by the 1918 Spanish Influenza pandemic. Students consider whether t ...


Zombie Attack!

Students assume the roles of CDC researchers who must determine how to most effectively stop an impending Zombie apocalypse. The story line leads s ...